PhD position in bioinformatics, next-generation sequencing, and cancer genomics at the Center for Human Genetics, Kuleuven

The Laboratory of Computational Biology together with the Laboratory for Molecular Pathogenesis of Leukemia have a joint position for a motivated PhD student interested in genomics and systems biology of cancer.

Research project
The PhD research will focus on high-throughput approaches to further decipher the leukemia genome and to identify novel oncogenic mutations or structural variations that may underlie tumorigenesis. Secondary interest goes out to variations in transcriptional networks and the characterization of the underlying cis-regulatory variations.

Available data include gene expression microarray data, GS FLX sequence data of candidate gene sets, and may even include full genome sequence data of
multiple cancer patients. The challenge of this project is to handle large amounts of public and in-house genomic data and to use, benchmark, and develop state-of-the- art bioinformatics approaches, while maintaining a clear focus on important biological questions.

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